We can apply our exceptional expertise in R&D, synthetic route development, scale-up synthesis, and analytical method development for cGMP manufacture to a broader range of pharmaceutical research areas.


Our Complex Chemistry Expertise:expertise image

  • Small molecules
  • Complex Carbohydrates
  • Dendrimers
  • Polymers
  • Nucleoside Analogs
  • Chemoenzymology & large scale fermentation
  • Peptidomimetics
  • Steroid analogs
  • Natural products
  • Oligosaccharides
  • Inositols
  • Phosphorylated compounds
  • Metabolites


As highly-experienced carbohydrate chemists and small molecule specialists, GlycoSyn has built a distinguished track record in chemo-enzymatic synthesis, and the development of enzyme inhibitors, vaccine adjuvants, and polymeric scaffolds to help advance the treatment of cancers and neurodegenerative diseases.


Areas suited to our capabilities include:

Rare disease market


  • We are working with some of the world’s largest orphan drug companies to manufacture cGMP-grade commercial ingredients, advanced intermediates and small molecule drugs/therapeutics.

Process development & redevelopment


  • We bring considerable process development expertise to helping our clients boost the efficiency of their synthetic processes for both small and large molecules.  

Polymers, Glycopolymers, and Dendrimers


  • GlycoSyn has extensive experience in the manufacture of high quality GMP polymeric scaffolds, which have garnered successful IND submissions. This includes a successful IND with US FDA for first discrete dendrimer construct, as well as multiple polymers currently in PI to III clinical trials.

Analytical standards


  • We can replicate existing analytical standards or develop new ones to help promote more accurate patient screening and efficient treatments.
  • We routinely prepare analytical standards for our clients. These standards include deuterium-labelled compounds, impurity markers, enantiomeric standards and highly purified and characterized reference standards.

Drug Metabolites


  • We carry out enzymatic glucuronidation reactions on compounds in a way that mimics the processes occurring naturally in our bodies and then purify the resultant products for use as analytical standards.
  • We have experience in production of glucuronides from milligram to gram scale using either synthetic or enzymatic methodologies.
  • Our in-house NMR, UPLC, and LCMS facilities ensure we can provide material that meets tight client specifications for identity and purity.