Kifunensine
5mg, $400
10mg, $600
50mg, $1,000
100mg, $1,500
250mg, $2,500
(5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione.
An alkaloid produced by the fungus, Kitasatosporia kifunense, kifunensine is a potent inhibitor of the mannosidase I enzyme (50 to 100 times more potent than deoxymannojirimycin). While ineffective against mannosidase II or the endoplasmic reticulum alpha-mannosidase, it has also been shown to weakly inhibit arylmannosidase.1,2
Larger quantities available for immediate shipment.
1. Iwami, M.; Nakayama, O.; Terano, H. J. Antibiotics 1987, 40, 612-622.
2. Elbein, A. D.; Tropea, J. E.; Mitchell, M.; Kaushal, G. P. J. Biol. Chem. 1990, 265, 15599-15605.
Larger quantities are available - please enquire.
